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Cytokine produced by recombinant riceOUR TECHNOLOGIES&PRODUCTS

Company profile

  PrevenTec, Inc. have developed methods for cytokine production by recombinant rice. Recombinant protein production in transgenic rice systems is an excellent technology in terms of cost benefit and safety. There is no contamination of animal components and bacterial components in the proteins produced in rice seed. PrevenTec, Inc. can provide a high quality recombinant proteins for clients.。

Technology

 We developed recombinant rice strains which express cytokines. Then we developed the procedure for extraction and purification of a cytokine from rice seed. The cytokines purified from rice seed have high activity upon susceptible cells and contain less than 10^-5EU/μg of endotoxin.


References

Fujiwara Y., Aiki Y., Yang L., Takaiwa F., Kosaka A., Tsuji N.M., Shiraki K. and Sekikawa K. (2010) Extraction and purification of human interleukin-10 from transgenic rice seeds. Protein Expr. Purif. 72, 125-130.
Fujiwara Y., Yang L., Takaiwa F., Sekikawa K.(2016) Expression and purification of recombinant mouse interleukin-4 and 6 from transgenic rice seeds. Molec. Biotech. 58(4), 223-231.
Takaiwa F, Wakasa Y, Ozawa K, Sekikawa K. (2021) Improvement of production yield and extraction efficacy of recombinant protein by high endosperm-specific expression along with simultaneous suppression of major seed storage proteins. Plant Sci. 302:110692.

Bussiness

  We can provide growth factors which can be used for cell culture of regenerative medicine research. bFGF and PDGF are available now. Cytokines for immunology studies are also on sale, IL-10, mouse IL-4 and mouse IL-6. We are also developing new products: aFGF, transferrin, and TGF-beta. They will be released in the near future.

Products

Brochure for Preventec cytokines






バナースペース

Preventec, Inc.

4-3-8Chuo, Ami, Inashiki
Ibaraki 300-0332, Japan

TEL: 029-846-1051